28 articles for thisTarget
The following articles (labelled with PubMed ID or TBD) are for your review
PMID
Data
Article Title
Organization
Inhibitors of Influenza Virus Polymerase Acidic (PA) Endonuclease: Contemporary Developments and Perspectives.
Shandong University
Polymerase Acidic Protein-Basic Protein 1 (PA-PB1) Protein-Protein Interaction as a Target for Next-Generation Anti-influenza Therapeutics.
University of Perugia
Structural and computational study on inhibitory compounds for endonuclease activity of influenza virus polymerase.
Chiba University
Inhibition of cap (m7GpppXm)-dependent endonuclease of influenza virus by 4-substituted 2,4-dioxobutanoic acid compounds.
Merck Research Laboratories
Synthesis of natural flutimide and analogous fully substituted pyrazine-2,6-diones, endonuclease inhibitors of influenza virus.
Merck Research Laboratories
Anti-influenza virus activities of 4-substituted 2,4-dioxobutanoic acid inhibitors.
Merck Research Laboratories
Identification of influenza endonuclease inhibitors using a novel fluorescence polarization assay.
University of Tennessee Health Science Center
Tetramic and tetronic acids: an update on new derivatives and biological aspects.
University of Bayreuth
Bioisosteres of the Phenyl Ring: Recent Strategic Applications in Lead Optimization and Drug Design.
Biocon-Bristol Myers Squibb Research and Development Centre
Geminal Diheteroatomic Motifs: Some Applications of Acetals, Ketals, and Their Sulfur and Nitrogen Homologues in Medicinal Chemistry and Drug Design.
Bristol Myers Squibb Research and Early Development
Discovery and optimization of new 6, 7-dihydroxy-1, 2, 3, 4-tetrahydroisoquinoline derivatives as potent influenza virus PA
South China Agricultural University
Anchor-GRIND: filling the gap between standard 3D QSAR and the GRid-INdependent descriptors.
Imim/Universitat Pompeu Fabra
Discovery of thiophene-2-carboxylic acids as potent inhibitors of HCV NS5B polymerase and HCV subgenomic RNA replication. Part 2: tertiary amides.
Shire Biochem
Discovery of thiophene-2-carboxylic acids as potent inhibitors of HCV NS5B polymerase and HCV subgenomic RNA replication. Part 1: Sulfonamides.
Shire Biochem
Further SAR studies on novel small molecule inhibitors of the hepatitis C (HCV) NS5B polymerase.
Shire Biochem
Use of a pharmacophore model to discover a new class of influenza endonuclease inhibitors.
Roche Discovery Welwyn
Glycine alpha-ketoamides as HCV NS3 protease inhibitors.
Pharmaceutical Research Institute
Evolution, synthesis and SAR of tripeptide alpha-ketoacid inhibitors of the hepatitis C virus NS3/NS4A serine protease.
Irbm, Mrl Rome
Fragment-Based Identification of Influenza Endonuclease Inhibitors.
University of California San Diego
SAR Exploration of Tight-Binding Inhibitors of Influenza Virus PA Endonuclease.
University of California
Synthesis and SAR Study of Carbamoyl Pyridone Bicycle Derivatives as Potent Inhibitors of Influenza Cap-dependent Endonuclease.
Shionogi
Non-chelating p-phenylidene-linked bis-imidazoline analogs of known influenza virus endonuclease inhibitors: Synthesis and anti-influenza activity.
Saint Petersburg State University
